CHO-MK*) host cell line which is banked as a host cell bank for the production of biopharmaceuticals, is our CHO host cell line developed from the primary cell culture of a healthy Chinese hamster ovary tissue for industrial applications. CHO-MK has demonstrated a remarkably higher productivity when compared to the conventional CHO host cell line. *)CHO-MK cells were developed under the support of AMED (Grant Number JP18ae101054)